Sequence-Selective Formation of Synthetic H-Bonded Duplexes

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Sequence-Selective Formation of Synthetic H-Bonded Duplexes

Oligomers equipped with a sequence of phenol and pyridine N-oxide groups form duplexes via H-bonding interactions between these recognition units. Reductive amination chemistry was used to synthesize all possible 3-mer sequences: AAA, AAD, ADA, DAA, ADD, DAD, DDA, and DDD. Pairwise interactions between the oligomers were investigated using NMR titration and dilution experiments in toluene. The ...

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ژورنال

عنوان ژورنال: Journal of the American Chemical Society

سال: 2017

ISSN: 0002-7863,1520-5126

DOI: 10.1021/jacs.7b06619